Sphingolipids are well-established regulators of cellular organization, signalling, metabolism, and disease. Far from serving solely as structural membrane components, these molecules actively shape membrane properties, coordinate communication between organelles, integrate metabolic and environmental signals, and influence cellular fate. At the same time, advances in lipidomics, chemical biology, spatial mass spectrometry, biosensors, and high-resolution imaging are revealing an increasingly complex and dynamic sphingolipid landscape.
The 4th edition of the ÂÌñÉçÇø Special Meeting on Sphingolipid Biology: Architects of the Cellular Landscape will provide a focused international forum for presenting and discussing the latest developments in the field. The meeting will bring together researchers working across structural biophysics, membrane biology, lipid metabolism, systems biology, and pathophysiology, fostering dialogue between disciplines that have traditionally approached sphingolipid biology from different perspectives.
The scientific programme will explore the molecular and analytical tools transforming sphingolipid research, the role of sphingolipids in membrane asymmetry and trafficking, their contribution to organelle communication and cellular architecture, and their function as metabolic circuits controlling cellular decisions. It will address how disruption of these processes contributes to human diseases while highlighting emerging opportunities for therapeutic intervention. A forward-looking final session will create space to discuss unexpected findings, unresolved questions, methodological limitations, and new directions for the field.
Extended discussion periods, poster sessions, flash presentations, and interactive panels will promote active participation across career stages, giving early-career researchers opportunities to engage with established investigators and contribute to the scientific dialogue. By combining broad scientific coverage with an inclusive and highly interactive format, the meeting aims to support the next generation of Sphingolipid researchers and help shape future directions in the field.
The meeting will take place from 6–11 June 2027 at the MH Atlântico Congress Centre in Peniche, Portugal. Its integrated conference and accommodation setting will provide an ideal environment for scientific exchange and informal interaction throughout the week.
We look forward to welcoming you to Peniche for an inspiring week of science!
The website for this course is under construction. Read this  for more information from the co-organizers.
Organizers: Liana C. Silva, Chris Clarke & Giovanni D’Angelo